A genomic view of eukaryotic DNA replication

@article{MacAlpine2005AGV,
  title={A genomic view of eukaryotic DNA replication},
  author={David M. MacAlpine and Stephen P Bell},
  journal={Chromosome Research},
  year={2005},
  volume={13},
  pages={309-326}
}
Recent advances in DNA microarray technology have enabled eukaryotic replication to be studied at whole-chromosome and genome-wide levels. These studies have provided new insights into the mechanisms that influence origin selection and the temporally co-ordinated activation of replication initiation from these sites. Here we describe multiple microarray-based approaches that have been used to study DNA replication in both S. cerevisiae and higher eukaryotes. We have also compiled the data from… CONTINUE READING
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