A genomic strategy to refine prognosis in early stage non-small cell lung carcinoma (NSCLC).

@article{Harpole2006AGS,
  title={A genomic strategy to refine prognosis in early stage non-small cell lung carcinoma (NSCLC).},
  author={David Harold Harpole and Rebecca P. Petersen and Sambuddho Mukherjee and Andrea Bild and Holly Dressman and Robert Arthur Kratzke and Michael J. Kelley and Jennifer W. Garst and Jeffrey Crawford and J. R. Nevins and A. De Potti},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2006},
  volume={24 18_suppl},
  pages={7026}
}
7026 Background. Although stage-specific classification identifies appropriate populations for adjuvant chemotherapy, this is likely an imprecise predictor for the individual patient with early stage NSCLC. METHODS Using previously-described methodologies that employ DNA microarray data, multiple gene expression profiles ('metagenes') that predict risk of recurrence in patients with stage I disease were identified. This analysis used an initial 'test' cohort of patients with NSCLC (n = 89… CONTINUE READING