A genome-wide survey of Major Histocompatibility Complex (MHC) genes and their paralogues in zebrafish

@article{Sambrook2005AGS,
  title={A genome-wide survey of Major Histocompatibility Complex (MHC) genes and their paralogues in zebrafish},
  author={Jennifer G. Sambrook and Felipe Figueroa and Stephan Beck},
  journal={BMC Genomics},
  year={2005},
  volume={6},
  pages={152 - 152}
}
The genomic organisation of the Major Histocompatibility Complex (MHC) varies greatly between different vertebrates. In mammals, the classical MHC consists of a large number of linked genes (e.g. greater than 200 in humans) with predominantly immune function. In some birds, it consists of only a small number of linked MHC core genes (e.g. smaller than 20 in chickens) forming a minimal essential MHC and, in fish, the MHC consists of a so far unknown number of genes including non-linked MHC core… CONTINUE READING
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