A genome-wide scan for primary open-angle glaucoma (POAG): the Barbados Family Study of Open-Angle Glaucoma

@article{Nemesure2003AGS,
  title={A genome-wide scan for primary open-angle glaucoma (POAG): the Barbados Family Study of Open-Angle Glaucoma},
  author={Barbara Nemesure and Xiaodong Jiao and Qimei He and Maria Cristina Leske and S Y Wu and Anselm J. M. Hennis and Nancy Mendell and Joy Redman and Henri-Jean Garchon and Richa Agarwala and Alejandro A. Sch{\"a}ffer and Fielding Hejtmancik and Barbados Family Study Group},
  journal={Human Genetics},
  year={2003},
  volume={112},
  pages={600-609}
}
Primary open-angle glaucoma (POAG) is characterized by damage to the optic nerve with associated loss of vision. Six named genetic loci have been identified as contributing to POAG susceptibility by genetic linkage analysis of mostly Caucasian families, and two of the six causative genes have been identified. The Barbados Family Study of Open-Angle Glaucoma (BFSG) was designed to evaluate the genetic component of POAG in a population of African descent. A genome-wide scan was performed on 1327… CONTINUE READING

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