A genome-wide nanotoxicology screen of Saccharomyces cerevisiae mutants reveals the basis for cadmium sulphide quantum dot tolerance and sensitivity.

@article{Marmiroli2016AGN,
  title={A genome-wide nanotoxicology screen of Saccharomyces cerevisiae mutants reveals the basis for cadmium sulphide quantum dot tolerance and sensitivity.},
  author={Marta Marmiroli and Luca Pagano and Francesco Pasquali and A. Zappettini and Valentina Tosato and Carlo V. Bruschi and Nelson Marmiroli},
  journal={Nanotoxicology},
  year={2016},
  volume={10 1},
  pages={84-93}
}
The use of cadmium sulphide quantum dots (CdS QDs) is increasing, particularly in the electronics industry. Their size (1-10 nm in diameter) is, however, such that they can be taken up by living cells. Here, a bakers' yeast (Saccharomyces cerevisiae) deletion mutant collection has been exploited to provide a high-throughput means of revealing the genetic basis for tolerance/susceptibility to CdS QD exposure. The deletion of 112 genes, some associated with the abiotic stress response, some with… CONTINUE READING
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