A genome-wide expression analysis in blood identifies pre-elafin as a biomarker in ARDS.

@article{Wang2008AGE,
  title={A genome-wide expression analysis in blood identifies pre-elafin as a biomarker in ARDS.},
  author={Zhaoxi Wang and Douglas Beach and Li Su and Rihong Zhai and David C. Christiani},
  journal={American journal of respiratory cell and molecular biology},
  year={2008},
  volume={38 6},
  pages={
          724-32
        }
}
Previous microarray-based studies of acute respiratory distress syndrome (ARDS) were performed using various models to mimic disease pathogenesis. The complexity of the pathophysiologic response to direct or indirect lung injury in ARDS is difficult to reconstruct in experimental conditions. Thus, direct analysis of ARDS patient blood may provide valuable information. We investigated genome-wide gene expression profiles in paired whole blood samples from patients with ARDS (n = 8) during the… CONTINUE READING
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