A genome-wide association study of schizophrenia using brain activation as a quantitative phenotype.

@article{Potkin2009AGA,
  title={A genome-wide association study of schizophrenia using brain activation as a quantitative phenotype.},
  author={Steven G. Potkin and Jessica A. Turner and Guia Guffanti and Anita Lakatos and James H. Fallon and Dana D Nguyen and Daniel H. Mathalon and Judith O'Malley Ford and John Lauriello and Fabio Macciardi},
  journal={Schizophrenia bulletin},
  year={2009},
  volume={35 1},
  pages={96-108}
}
BACKGROUND Genome-wide association studies (GWASs) are increasingly used to identify risk genes for complex illnesses including schizophrenia. These studies may require thousands of subjects to obtain sufficient power. We present an alternative strategy with increased statistical power over a case-control study that uses brain imaging as a quantitative trait (QT) in the context of a GWAS in schizophrenia. METHODS Sixty-four subjects with chronic schizophrenia and 74 matched controls were… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 97 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 89 references

Similar Papers

Loading similar papers…