A genome-wide association study of early spontaneous preterm delivery.

  title={A genome-wide association study of early spontaneous preterm delivery.},
  author={Heping Zhang and Don A. Baldwin and Radek K Bukowski and Samuel Parry and Yaji Xu and Chi Song and William W. Andrews and George R. Saade and Michael Sean Esplin and Yoel Sadovsky and Uma Maheswara Reddy and John V. Ilekis and Michael Varner and Joseph R Biggio},
  journal={Genetic epidemiology},
  volume={39 3},
Preterm birth is the leading cause of infant morbidity and mortality. Despite extensive research, the genetic contributions to spontaneous preterm birth (SPTB) are not well understood. Term controls were matched with cases by race/ethnicity, maternal age, and parity prior to recruitment. Genotyping was performed using Affymetrix SNP Array 6.0 assays. Statistical analyses utilized PLINK to compare allele occurrence rates between case and control groups, and incorporated quality control and… CONTINUE READING