A genome-wide association study of a coronary artery disease risk variant

  title={A genome-wide association study of a coronary artery disease risk variant},
  author={Ji-Young Lee and Bok-Soo Lee and Dong-jik Shin and Kyung Woo Park and Young-Ah Shin and Kwang Joong Kim and Lyong Heo and Ji Young Lee and Yun Kyoung Kim and Young Jin Kim and Chang Bum Hong and Sang Hak Lee and Dankyu Yoon and Hyo Jung Ku and Il Young Oh and Bong-Jo Kim and Juyoung Lee and Seon-Joo Park and Jimin Kim and Hye-kyung Kawk and Jong-Eun Lee and Hye-kyung Park and Jae-eun Lee and Hye-young Nam and Hyun-young Park and Chol Shin and Mitsuhiro Yokota and Hiroyuki Asano and Masahiro Nakatochi and Tatsuaki Matsubara and Hidetoshi Kitajima and Ken Yamamoto and Hyung-Lae Kim and Bok-ghee Han and Myeong Chan Cho and Yangsoo Jang and Hyo Soo Kim and Jeong Euy Park and Jong-Young Lee},
  journal={Journal of Human Genetics},
Although over 30 common genetic susceptibility loci have been identified to be independently associated with coronary artery disease (CAD) risk through genome-wide association studies (GWAS), genetic risk variants reported to date explain only a small fraction of heritability. To identify novel susceptibility variants for CAD and confirm those previously identified in European population, GWAS and a replication study were performed in the Koreans and Japanese. In the discovery stage, we… CONTINUE READING
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