A genome-wide association study identifies a region strongly associated with symmetrical onychomadesis on chromosome 12 in dogs.

@article{Dahlgren2016AGA,
  title={A genome-wide association study identifies a region strongly associated with symmetrical onychomadesis on chromosome 12 in dogs.},
  author={S. Dahlgren and M. Ziener and F. Lingaas},
  journal={Animal genetics},
  year={2016},
  volume={47 6},
  pages={
          708-716
        }
}
  • S. Dahlgren, M. Ziener, F. Lingaas
  • Published 2016
  • Biology, Medicine
  • Animal genetics
  • Symmetrical onychomadesis causes periodic loss of claws in otherwise healthy dogs. Genome-wide association analysis in 225 Gordon Setters identified a single region associated with symmetrical onychomadesis on chromosome 12 (spanning about 3.3 mb). A meta-analysis including also English Setters indicated that this genomic region predisposes for symmetrical onychomadesis in English Setters as well. The associated region spans most of the major histocompatibility complex and nearly 1 Mb… CONTINUE READING
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