A genome-wide association study for age-related hearing impairment in the Saami

@article{Laer2010AGA,
  title={A genome-wide association study for age-related hearing impairment in the Saami},
  author={Lut Van Laer and Jeroen R Huyghe and Samuli Hannula and Els Van Eyken and Dietrich A. Stephan and Elina Margareetta M{\"a}ki-Torkko and Pekka Aikio and Erik Frans{\'e}n and Alana Lysholm-Bernacchi and Martti Sorri and Matthew J. Huentelman and Guy Van Camp},
  journal={European Journal of Human Genetics},
  year={2010},
  volume={18},
  pages={685-693}
}
This study aimed at contributing to the elucidation of the genetic basis of age-related hearing impairment (ARHI), a common multifactorial disease with an important genetic contribution as demonstrated by heritability studies. We conducted a genome-wide association study (GWAS) in the Finnish Saami, a small, ancient, genetically isolated population without evidence of demographic expansion. The choice of this study population was motivated by its anticipated higher extent of LD, potentially… CONTINUE READING