A genome-wide association analysis identifies PDE1A|DNAJC10 locus on chromosome 2 associated with idiopathic pulmonary arterial hypertension in a Japanese population

Abstract

Pulmonary arterial hypertension (PAH) is a lethal disease that often affects the young. Although Bone Morphogenetic Protein Receptor Type 2 gene (BMPR2) mutations are related with idiopathic and heritable PAH, the low penetrance and variable expressivity in PAH suggest the existence of other genetic and/or environmental factors. In this study, we aimed to… (More)
DOI: 10.18632/oncotarget.20459

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@inproceedings{Kimura2017AGA, title={A genome-wide association analysis identifies PDE1A|DNAJC10 locus on chromosome 2 associated with idiopathic pulmonary arterial hypertension in a Japanese population}, author={Mai Kimura and Yuichi Tamura and Christophe Guignabert and Makoto Takei and Kenjiro Kosaki and Nobuhiro Tanabe and Koichiro Tatsumi and Tsutomu T Saji and Toru Satoh and Masaharu Kataoka and Shigeo Kamitsuji and Naoyuki Kamatani and Rapha{\"{e}l Thuillet and Ly Tu and Marc Humbert and Keiichi Fukuda and Motoaki Sano}, booktitle={Oncotarget}, year={2017} }