A genetically immortalized human stem cell line: a promising new tool for Alzheimer's disease therapy.

Abstract

Amyloid-β peptides and hyper-phosphorylated tau are the main pathological hallmarks of Alzheimer's disease (AD). Given the recent failure of several large-scale clinical trials and the lack of disease-modifying pharmacological treatments, there is an urgent need to develop alternative therapies. A clinical grade human CTX0E03 neural stem cell line has… (More)
DOI: 10.17179/excli2015-560

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