A genetic variant near olfactory receptor genes influences cilantro preference
@article{Eriksson2012AGV, title={A genetic variant near olfactory receptor genes influences cilantro preference}, author={Nicholas Eriksson and Shirley Wu and Chuong B. Do and Amy K. Kiefer and Joyce Y. Tung and Joanna L. Mountain and David A. Hinds and Uta Francke}, journal={Flavour}, year={2012}, volume={1}, pages={1-7} }
BackgroundThe leaves of the Coriandrum sativum plant, known as cilantro or coriander, are widely used in many cuisines around the world. However, far from being a benign culinary herb, cilantro can be polarizing—many people love it while others claim that it tastes or smells foul, often like soap or dirt. This soapy or pungent aroma is largely attributed to several aldehydes present in cilantro. Cilantro preference is suspected to have a genetic component, yet to date nothing is known about…
82 Citations
Sequence Variants in TAAR5 and Other Loci Affect Human Odor Perception and Naming
- BiologyCurrent Biology
- 2020
Influence of genetic variation on flavour perception and food choices
- Biology
- 2018
Some mechanisms involved in systematic variation in chemosensation across individuals are reviewed, and a few examples that are relevant to ingestive behavior, food choice, and consumer behavior are highlighted.
Complex relationship between TAS2 receptor variations, bitterness perception, and alcohol consumption observed in a population of wine consumers.
- MedicineFood & function
- 2019
In a survey of 519 participants, almost all of whom regularly consumed alcohol, it was observed that genetic variants in TAS2R38 were significantly associated with both increased alcohol consumption and the ability to perceive bitterness in several foods and a bitter chemical.
Do polymorphisms in chemosensory genes matter for human ingestive behavior?
- BiologyFood quality and preference
- 2013
Identification of Regions Associated with Variation in Sensitivity to Food-Related Odors in the Human Genome
- Biology, PsychologyCurrent Biology
- 2013
Landscape of Variability in Chemosensory Genes Associated With Dietary Preferences in Indian Population: Analysis of 1029 Indian Genomes
- BiologyFrontiers in Genetics
- 2022
This is a first of its kind study on baseline variations in genes that could govern cuisine designs, dietary preferences and health outcomes of enormous utility in dietary recommendations for precision nutrition both at population and individual level.
The Missense of Smell: Functional Variability in the Human Odorant Receptor Repertoire
- BiologyNature Neuroscience
- 2014
To show that in vitro results are relevant to olfactory perception, it is verified that variations in OR10G4 genotype explain over 15% of the observed variation in perceived intensity and over 10% in perceived valence for the high-affinity in vitro agonist guaiacol but do not explain phenotype variation for the lower-Affinity agonists vanillin and ethyl vanillin.
Do you smell what I smell? Genetic variation in olfactory perception.
- BiologyBiochemical Society transactions
- 2014
The evidence that OR genes are extremely variable between individuals is reviewed and it is argued that this contributes to a unique receptor repertoire in the authors' noses that provides us each with a personalized perception of their environment.
Genetic variation across the human olfactory receptor repertoire alters odor perception
- Biology, PsychologyProceedings of the National Academy of Sciences
- 2019
It is demonstrated how natural variation can provide important clues to the normal translation of OR activation to odor information and places a constraint on the amount of redundancy in the olfactory code.
Odour hedonics and the ubiquitous appeal of vanilla
- Nature Food
- 2022
Our food choices and consumption behaviours are often influenced by odour hedonics, especially in the case of those orthonasally experienced aromas (that is, those odours that are food-related). The…
References
SHOWING 1-10 OF 37 REFERENCES
Genetic analysis of chemosensory traits in human twins.
- BiologyChemical senses
- 2012
It is demonstrated that person-to-person differences in the taste and smell perception of simple foods and drinks are partially accounted for by genetic variation within chemosensory pathways.
Positional Cloning of the Human Quantitative Trait Locus Underlying Taste Sensitivity to Phenylthiocarbamide
- BiologyScience
- 2003
A small region on chromosome 7q that shows strong linkage disequilibrium between single-nucleotide polymorphism (SNP) markers and PTC taste sensitivity in unrelated subjects and a single gene that encodes a member of the TAS2R bitter taste receptor family is identified.
Prevalence of cilantro (Coriandrum sativum) disliking among different ethnocultural groups
- MedicineFlavour
- 2011
These findings show that the prevalence of cilantro dislike differs widely between various ethnocultural groups.
Genetic variation in a human odorant receptor alters odour perception
- BiologyNature
- 2007
It is shown that a human odorant receptor, OR7D4, is selectively activated in vitro by androstenone and the related odorous steroid androstadienone and does not respond to a panel of 64 other odours and two solvents.
Characteristic aroma components of the cilantro mimics
- Chemistry
- 2005
Aroma profiles of fresh herbs of cilantro (Coriandrum sativum L.), culantro (Eryngium foetidum L.) and Vietnamese coriander (Polygonium odoratum L.) were compared by direct solvent extraction, gas…
A pharmacological profile of the aldehyde receptor repertoire in rat olfactory epithelium
- BiologyThe Journal of physiology
- 2004
A large number of receptors for octanal suggests that, although the peripheral olfactory system is endowed with high sensitivity, discrimination among different compounds probably requires further central processing.
Genetics of taste and smell: poisons and pleasures.
- Medicine, BiologyProgress in molecular biology and translational science
- 2010
Identification of Ligands for Olfactory Receptors by Functional Expression of a Receptor Library
- BiologyCell
- 1998
Hundreds of variants clustered in genomic loci and biological pathways affect human height
- BiologyNature
- 2010
It is shown that hundreds of genetic variants, in at least 180 loci, influence adult height, a highly heritable and classic polygenic trait, and indicates that GWA studies can identify large numbers of loci that implicate biologically relevant genes and pathways.