A genetic study of chronic venous insufficiency.

  title={A genetic study of chronic venous insufficiency.},
  author={Raffaele Serra and Gianluca Buffone and Andrea de Franciscis and Diego Mastrangelo and Vincenzo Molinari and Rossella Montemurro and Stefano de Franciscis},
  journal={Annals of vascular surgery},
  volume={26 5},
BACKGROUND Chronic venous insufficiency (CVI) is an important cause of morbidity in Western countries. The aim of this study is to demonstrate the heredity of CVI, focusing on molecular and genetic aspects of the disease. METHODS The study depended on the recruitment of informative families, accurate determination of the phenotype of each family member, and blood sample for DNA extraction for genetic analysis. Each family member was invited to attend a vascular consultation. A genealogical… CONTINUE READING


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