A genetic study of Parkinson's disease.

  title={A genetic study of Parkinson's disease.},
  author={Giuseppe De Michele and Alessandro Filla and R Marconi and Giampiero Volpe and Adele D'Alessio and Rossana Scala and Gennaro Ambrosio and Giuseppe Campanella},
  journal={Journal of neural transmission. Supplementum},
We performed a case-control study on 100 patients with Parkinson's disease, their spouses and the same number of sex- and age-matched neurological controls to clarify if family history of Parkinson's disease or essential tremor may increase the risk for the disease. We included in the study 68 male and 32 female parkinsonian patients with a mean age +/- SD of 62.0 +/- 9.9 years and a mean disease duration of 7.5 +/- 5.7. The odds ratio for familial Parkinson's disease was 13.4 (95% confidence… CONTINUE READING