A genetic screen identifies new regulators of steroid-triggered programmed cell death in Drosophila.

@article{Wang2008AGS,
  title={A genetic screen identifies new regulators of steroid-triggered programmed cell death in Drosophila.},
  author={Lei Wang and Janelle Evans and Hillary K Andrews and Robert B. Beckstead and Carl S Thummel and Arash Bashirullah},
  journal={Genetics},
  year={2008},
  volume={180 1},
  pages={269-81}
}
The steroid hormone ecdysone triggers the rapid and massive destruction of larval tissues through transcriptional cascades that culminate in rpr and hid expression and caspase activation. Here we describe the use of genetic screens to further our understanding of this steroid-triggered programmed cell death response. Pupal lethal mutants were screened for… CONTINUE READING