A genetic schizophrenia-susceptibility region located between the ANKK1 and DRD2 genes

@article{Dubertret2010AGS,
  title={A genetic schizophrenia-susceptibility region located between the ANKK1 and DRD2 genes},
  author={Caroline Dubertret and Claire Bardel and Nicolas Ramoz and Pierre-Marie Martin and Laurent Gouya},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={2010},
  volume={34},
  pages={492-499}
}
BACKGROUND The gene coding for the D2 dopamine receptor (DRD2) is considered to be one of the most pertinent candidate genes in schizophrenia. However, genetic studies have yielded conflicting results whereas the promising TaqIA variant/rs1800497 has been mapped in a novel gene, ANKK1. METHODS We investigated eleven single nucleotide polymorphisms (SNPs) spanning the DRD2 and ANKK1 genes, using both a case-control association study comparing 144 independent patients to 142 matched healthy… CONTINUE READING
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