A general review of the role of irinotecan (CPT11) in the treatment of gastric cancer.

@article{Farhat2007AGR,
  title={A general review of the role of irinotecan (CPT11) in the treatment of gastric cancer.},
  author={Fadi Sami Farhat},
  journal={Medical oncology},
  year={2007},
  volume={24 2},
  pages={137-46}
}
BACKGROUND The prognosis of gastric tumor is generally poor because most tumors are diagnosed at an advanced stage. Chemotherapy has a proven palliative role in advanced gastric cancer and several combination regimens were explored in the last 10 yr. Nevertheless, none of them showed a convincing improvement resulting in an enhancement of response rate and overall survival without discrimination of the quality of life. Irinotecan (CPT11) has been evaluated in multiple trials alone or in… CONTINUE READING
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