A general overview of the use of ibuprofen in paediatrics.

  title={A general overview of the use of ibuprofen in paediatrics.},
  author={Elisabeth Autret-Leca},
  journal={International journal of clinical practice. Supplement},
Ibuprofen is prescribed for children for the treatment of acute pain and fever, and for juvenile idiopathic arthritis. The pharmacokinetic characteristics of ibuprofen in children are similar to those in adults and the relationship between dose and response is linear over the range 5-10 mg/kg. Clinical trials of ibuprofen have shown the effective dose range to be 7.5-10 mg/kg. The maximum reduction in temperature occurs 3-4 hours after administration. In comparative clinical trials, ibuprofen… CONTINUE READING