A general model to optimise CuII labelling efficiency of double-histidine motifs for pulse dipolar EPR applications.

@article{Wort2021AGM,
  title={A general model to optimise CuII labelling efficiency of double-histidine motifs for pulse dipolar EPR applications.},
  author={J. Wort and Katrin Ackermann and D. Norman and B. Bode},
  journal={Physical chemistry chemical physics : PCCP},
  year={2021}
}
Electron paramagnetic resonance (EPR) distance measurements are making increasingly important contributions to studies of biomolecules underpinning health and disease by providing highly accurate and precise geometric constraints. Combining double-histidine (dH) motifs with CuII spin labels shows promise for further increasing the precision of distance measurements, and for investigating subtle conformational changes. However, non-covalent coordination-based spin labelling is vulnerable to low… Expand
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