A general model for the surface glycoproteins of HIV and other retroviruses.

@article{Gallaher1995AGM,
  title={A general model for the surface glycoproteins of HIV and other retroviruses.},
  author={William R. Gallaher and J M Ball and Robert F Garry and A M Martin-Amedee and Ronald C. Montelaro},
  journal={AIDS research and human retroviruses},
  year={1995},
  volume={11 2},
  pages={191-202}
}
A hypothetical model of the surface (SU) glycoproteins of human immunodeficiency virus (HIV) and other retroviruses is proposed. The model is based on repetition of a limited number of sequence motifs conserved within the virus family; similarities in biological, immunological, or genetic properties; as well as the tendency for regions of dissimilar sequence to share protein structures predicted by computer algorithms. It is proposed that the protein consists of three structural and functional… CONTINUE READING

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