A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer.

Abstract

The homeobox gene hhex is one of the earliest markers of the anterior endoderm, which gives rise to foregut organs such as the liver, ventral pancreas, thyroid, and lungs. The regulatory networks controlling hhex transcription are poorly understood. In an extensive cis-regulatory analysis of the Xenopus hhex promoter, we determined how the Nodal, Wnt, and… (More)
DOI: 10.1016/j.ydbio.2010.11.037

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