A gene on SCA4 locus causes dominantly inherited pure cerebellar ataxia.

@article{Nagaoka2000AGO,
  title={A gene on SCA4 locus causes dominantly inherited pure cerebellar ataxia.},
  author={Utako Nagaoka and Minoru Takashima and Kinya Ishikawa and Kazuo Yoshizawa and Toshihiro Yoshizawa and Mayuko Ishikawa and Takemori Yamawaki and Shin'ichi Shoji and Hidehiro Mizusawa},
  journal={Neurology},
  year={2000},
  volume={54 10},
  pages={1971-5}
}
BACKGROUND Several different genes or their loci have been identified for autosomal dominant cerebellar ataxia (ADCA). However, other types of ataxia remain unassigned. OBJECTIVE To identify a new locus for ADCA. METHODS Six Japanese families with ADCA with pure cerebellar syndrome (ADCA type III) were examined. These families had been molecularly excluded for spinocerebellar ataxia (SCA) types 1 through 3, 5 through 8, and 10. Clinical examination was undertaken, and a genome-wide linkage… CONTINUE READING