A gene for hereditary pancreatitis maps to chromosome 7q35.

  title={A gene for hereditary pancreatitis maps to chromosome 7q35.},
  author={David C. Whitcomb and Robert A. Preston and Christopher Eric Aston and Michael J. Sossenheimer and Purnima Barua and Yue-Ming Zhang and A Wong-Chong and Gerard J. White and Phillip G. Wood and Lawrence K. Gates and Charles D. Ulrich and Stephen P. Martin and James Christopher Post and Garth D. Ehrlich},
  volume={110 6},
BACKGROUND & AIMS Hereditary pancreatitis (HP) is an autosomal-dominant disorder with incomplete penetrance characterized by recurrent bouts of severe epigastric pain with onset usually at 5-10 years of age. A genetic linkage study was designed to identify the HP gene. METHODS A 500-member pedigree was constructed from a U.S. kindred centered in eastern Kentucky and western Virginia. A genome-wide search strategy was employed using a 36-member subset of this family to determine the genetic… CONTINUE READING
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