A gene for congenital generalized lipodystrophy maps to human chromosome 9q34.

@article{Garg1999AGF,
  title={A gene for congenital generalized lipodystrophy maps to human chromosome 9q34.},
  author={Abhimanyu Garg and Robert Wilson and R. Barnes and Elif Arioglu and Zohra Zaidi and Figen Gurakan and Nurten Koçak and Stephen O'Rahilly and Simeon I Taylor and Shailesh B Patel and Anne M Bowcock},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1999},
  volume={84 9},
  pages={3390-4}
}
Congenital generalized lipodystrophy (CGL, Berardinelli-Seip Syndrome, OMIM # 269700) is a rare autosomal recessive disorder characterized by near complete absence of adipose tissue from birth. Affected individuals have marked insulin resistance, hypertriglyceridemia and acanthosis nigricans, and develop diabetes mellitus during teenage years. The genetic defect for CGL is unknown. A semi-automated genome-wide scan with a set of highly polymorphic short tandem repeats (STR) was carried out in… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 59 extracted citations

Similar Papers

Loading similar papers…