A gene expression signature associated with survival in metastatic melanoma

@article{Mandruzzato2006AGE,
  title={A gene expression signature associated with survival in metastatic melanoma},
  author={Susanna Mandruzzato and Andrea Callegaro and Gianluca Turcatel and Samuela Francescato and Maria Cristina Montesco and Vanna Chiarion-Sileni and Simone Mocellin and Carlo Riccardo Rossi and Silvio Bicciato and Ena Wang and Francesco M. Marincola and Paola Zanovello},
  journal={Journal of Translational Medicine},
  year={2006},
  volume={4},
  pages={50 - 50}
}
BackgroundCurrent clinical and histopathological criteria used to define the prognosis of melanoma patients are inadequate for accurate prediction of clinical outcome. We investigated whether genome screening by means of high-throughput gene microarray might provide clinically useful information on patient survival.MethodsForty-three tumor tissues from 38 patients with stage III and stage IV melanoma were profiled with a 17,500 element cDNA microarray. Expression data were analyzed using… CONTINUE READING

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