A gene expression map of human chromosome 21 orthologues in the mouse

@article{initiative2002AGE,
  title={A gene expression map of human chromosome 21 orthologues in the mouse},
  author={The HSA21 expression map initiative},
  journal={Nature},
  year={2002},
  volume={420},
  pages={586-590}
}
The DNA sequence of human chromosome 21 (HSA21)1 has opened the route for a systematic molecular characterization of all of its genes. Trisomy 21 is associated with Down's syndrome, the most common genetic cause of mental retardation in humans. The phenotype includes various organ dysmorphies, stereotypic craniofacial anomalies and brain malformations2. Molecular analysis of congenital aneuploidies poses a particular challenge because the aneuploid region contains many protein-coding genes… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 55 CITATIONS, ESTIMATED 79% COVERAGE

The mouse genome sequence - the end of the tail, or just the beginning?

  • Genome Biology
  • 2003
VIEW 3 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Leveraging Online Resources to Prioritize Candidate Genes for Functional Analyses: Using the Fetal Testis as a Test Case.

  • Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation
  • 2017
VIEW 1 EXCERPT

FILTER CITATIONS BY YEAR

2003
2019

CITATION STATISTICS

  • 5 Highly Influenced Citations