A gene expression atlas of the central nervous system based on bacterial artificial chromosomes

@article{Gong2003AGE,
  title={A gene expression atlas of the central nervous system based on bacterial artificial chromosomes},
  author={S. Gong and Chen Zheng and Martin L. Doughty and K. Losos and N. Didkovsky and Uta B. Schambra and N. Nowak and A. Joyner and G. Leblanc and Mary E. Hatten and N. Heintz},
  journal={Nature},
  year={2003},
  volume={425},
  pages={917-925}
}
  • S. Gong, Chen Zheng, +8 authors N. Heintz
  • Published 2003
  • Medicine, Biology
  • Nature
  • The mammalian central nervous system (CNS) contains a remarkable array of neural cells, each with a complex pattern of connections that together generate perceptions and higher brain functions. Here we describe a large-scale screen to create an atlas of CNS gene expression at the cellular level, and to provide a library of verified bacterial artificial chromosome (BAC) vectors and transgenic mouse lines that offer experimental access to CNS regions, cell classes and pathways. We illustrate the… CONTINUE READING
    Gene Expression Nervous System Atlas (GENSAT)
    • 257
    • Open Access
    Genome-wide atlas of gene expression in the adult mouse brain
    • 3,667
    • Open Access
    BAC transgenic mice and the GENSAT database of engineered mouse strains.
    • 47
    Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types
    • 391
    • Open Access
    A Translational Profiling Approach for the Molecular Characterization of CNS Cell Types
    • 856
    • Open Access
    Adult mouse brain gene expression patterns bear an embryologic imprint.
    • 166
    • Open Access

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 49 REFERENCES
    Bac to the future: The use of bac transgenic mice for neuroscience research
    • 330
    • Open Access
    Histology of the nervous system of man and vertebrates
    • 276
    New Directions in Neuronal Migration
    • 217