A gene expression atlas of the central nervous system based on bacterial artificial chromosomes

  title={A gene expression atlas of the central nervous system based on bacterial artificial chromosomes},
  author={S. Gong and Chen Zheng and Martin L. Doughty and K. Losos and N. Didkovsky and Uta B. Schambra and N. Nowak and A. Joyner and G. Leblanc and Mary E. Hatten and N. Heintz},
  • S. Gong, Chen Zheng, +8 authors N. Heintz
  • Published 2003
  • Medicine, Biology
  • Nature
  • The mammalian central nervous system (CNS) contains a remarkable array of neural cells, each with a complex pattern of connections that together generate perceptions and higher brain functions. Here we describe a large-scale screen to create an atlas of CNS gene expression at the cellular level, and to provide a library of verified bacterial artificial chromosome (BAC) vectors and transgenic mouse lines that offer experimental access to CNS regions, cell classes and pathways. We illustrate the… CONTINUE READING
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