A gene cluster for secondary metabolism in oat: implications for the evolution of metabolic diversity in plants.

@article{Qi2004AGC,
  title={A gene cluster for secondary metabolism in oat: implications for the evolution of metabolic diversity in plants.},
  author={Xiaoquan Qi and Saleha Bakht and Mike Leggett and C. Christopher Maxwell and Rachel Melton and Anne Osbourn},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 21},
  pages={8233-8}
}
The evolution of the ability to synthesize specialized metabolites is likely to have been key for survival and diversification of different plant species. Oats (Avena spp.) produce antimicrobial triterpenoids (avenacins) that protect against disease. The oat beta-amyrin synthase gene AsbAS1, which encodes the first committed enzyme in the avenacin biosynthetic pathway, is clearly distinct from other plant beta-amyrin synthases. Here we show that AsbAS1 has arisen by duplication and divergence… CONTINUE READING

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