A gene atlas of ‘structural immunity’

@article{Minton2020AGA,
  title={A gene atlas of ‘structural immunity’},
  author={Kirsty Minton},
  journal={Nature Reviews Immunology},
  year={2020},
  volume={20},
  pages={518 - 519}
}
  • Kirsty Minton
  • Published 13 July 2020
  • Biology
  • Nature Reviews Immunology
Multi-omics profiling of endothelial cells, epithelial cells and fibroblasts from 12 mouse organs was used to create an atlas of immune gene activity in structural cells. 
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ncbi.nlm.nih.gov

References

Structural cells are key regulators of organ-specific immune response

This study highlights the prevalence and organ-specific complexity of immune gene activity in non-haematopoietic structural cells, and it provides a high-resolution, multi-omics atlas of the epigenetic and transcriptional networks that regulate structural cells in the mouse.