A gender comparison of postobstructive injury in the rat kidney.

@article{Quinlan2010AGC,
  title={A gender comparison of postobstructive injury in the rat kidney.},
  author={Mark R. Quinlan and Peter Cronin and P{\'a}draig J A Daly and Ronald W Watson and Walter A. F. Manucha and Neil G Docherty and John M. Fitzpatrick},
  journal={Kidney & blood pressure research},
  year={2010},
  volume={33 4},
  pages={266-73}
}
BACKGROUND/AIMS Unilateral ureteral obstruction (UUO) results in renal injury. Studies report increased injury indices in male rats following UUO. Our study examined whether this gender-based renal response to UUO was reflected in sustained differences following relief of obstruction. METHODS Adult male/female rats (200-400 g) were subjected to either sham surgery (S/RN) or UUO (UUO/RN). At 24 h, obstruction was relieved and all animals underwent contralateral nephrectomy. Five days after… CONTINUE READING