• DOI:10.2174/15672018113106660065
Corpus ID: 41654338

A gastroretentive drug delivery system of lisinopril imbibed on isabgol-husk.

@article{Semwal2014AGD,
  title={A gastroretentive drug delivery system of lisinopril imbibed on isabgol-husk.},
  author={R. Semwal and R. B. Semwal and D. Semwal},
  journal={Current drug delivery},
  year={2014},
  volume={11 3},
  pages={
          371-9
        }
}

R. Semwal, R. B. Semwal, D. Semwal

Published 2014

Chemistry, Medicine

Current drug delivery

The gastroretentive drug delivery system is site-specific and allows the drug to remain in the stomach for a prolonged period of time so that it can be released in a controlled manner in gastrointestinal tract. The present study was carried out to develop a gastroretentive drug delivery system using isabgol as an excipient to prolong the residence time of the model drug lisinopril in the stomach. The gastroretentive ability of isabgol was increased by addition of NaHCO3 as a gas-generating… CONTINUE READING

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