A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord

@article{Sun2007AGP,
  title={A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord},
  author={Yan-Gang Sun and Zhou-Feng Chen},
  journal={Nature},
  year={2007},
  volume={448},
  pages={700-703}
}
Itching, or pruritus, is defined as an unpleasant cutaneous sensation that serves as a physiological self-protective mechanism to prevent the body from being hurt by harmful external agents. Chronic itch represents a significant clinical problem resulting from renal diseases and liver diseases, as well as several serious skin diseases such as atopic dermatitis. The identity of the itch-specific mediator in the central nervous system, however, remains elusive. Here we describe that the gastrin… 
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