A galinstan expansion femtosyringe for microinjection of eukaryotic organelles and prokaryotes

@article{Knoblauch1999AGE,
  title={A galinstan expansion femtosyringe for microinjection of eukaryotic organelles and prokaryotes},
  author={M. Knoblauch and J. Hibberd and J. Gray and A. J. V. Bel},
  journal={Nature Biotechnology},
  year={1999},
  volume={17},
  pages={906-909}
}
  • M. Knoblauch, J. Hibberd, +1 author A. J. V. Bel
  • Published 1999
  • Medicine, Biology
  • Nature Biotechnology
  • A galinstan expansion femtosyringe enables femtoliter to attoliter samples to be introduced into prokaryotes and subcellular compartments of eukaryotes. The method uses heat-induced expansion of galinstan (a liquid metal alloy of gallium, indium, and tin) within a glass syringe to expel samples through a tip diameter of about 0.1 μm. The narrow tip inflicts less damage than conventional capillaries, and the heat-induced expansion of the galinstan allows fine control over the rate of injection… CONTINUE READING
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