A gain-of-function mutation in a cytokinin receptor triggers spontaneous root nodule organogenesis.

@article{Tirichine2007AGM,
  title={A gain-of-function mutation in a cytokinin receptor triggers spontaneous root nodule organogenesis.},
  author={Le{\"i}la Tirichine and Niels Sandal and Lene H. Madsen and Simona Radutoiu and Anita S. Albrektsen and Shusei Sato and Erika Asamizu and Satoshi Tabata and Jens Stougaard},
  journal={Science},
  year={2007},
  volume={315 5808},
  pages={104-7}
}
Legume root nodules originate from differentiated cortical cells that reenter the cell cycle and form organ primordia. We show that perception of the phytohormone cytokinin is a key element in this switch. Mutation of a Lotus japonicus cytokinin receptor gene leads to spontaneous development of root nodules in the absence of rhizobia or rhizobial signal molecules. The mutant histidine kinase receptor has cytokinin-independent activity and activates an Escherichia coli two-component phosphorelay… CONTINUE READING
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