A fuzzy guided genetic algorithm for operon prediction

  title={A fuzzy guided genetic algorithm for operon prediction},
  author={Elizabeth Jacob and Roschen Sasikumar and K. N. Ramachandran Nair},
  volume={21 8},
MOTIVATION The operon structure of the prokaryotic genome is a critical input for the reconstruction of regulatory networks at the whole genome level. As experimental methods for the detection of operons are difficult and time-consuming, efforts are being put into developing computational methods that can use available biological information to predict operons. METHOD A genetic algorithm is developed to evolve a starting population of putative operon maps of the genome into progressively… CONTINUE READING


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