A fungitoxic substance extracted from tulips and its possible role as a protectant against disease

  title={A fungitoxic substance extracted from tulips and its possible role as a protectant against disease},
  author={B. H. H. Bergman and J. C. M. Beijersbergen},
  journal={Netherlands Journal of Plant Pathology},
A specialized strain ofFusarium oxysporum is the cause of a disease important in tulip bulb cultivation. From observations in the field it was concluded that the fungus is not able to penetrate into the tulip bulb during the greater part of the growing season. A protecting barrier was demonstrated to be present in the white skin. From extracts of this white skin (and from other parts of the tulip plant) a fungitoxic substance was isolated, which was identified as α-methylene butyrolactone. A… 
Molecular diversity of tuliposide B-converting enzyme in tulip (Tulipa gesneriana): identification of the root-specific isozyme
Tissue-specific isozymes are involved in the conversion of 6-tuliposide B, a major secondary metabolite in tulip, to antibacterial tulipalin B, which encodes a TCEB.
Antibacterial effects of S-(-)-tulipalin B isolated from Spiraea thunbergii Sieb. on Escherichia coli, a major food borne pathogenic microorganism
The crude ethanol extract of the leaves of Spiraea thunbergii Sieb. (Rosaceae) showed antibacterial activity against a food borne pathogen, Escherichia coli. Bioactivity-guided separation led to the
Anther-specific Production of Antimicrobial Tuliposide B in Tulips
The results suggest that a novel defense strategy evolved in tulips to protect pollens from bacterial pollution in the reproductive process by producing an anther-specific 6-tuliposide B.
Tulipalin A induced phytotoxicity
A case of Tulipalin A induced phytotoxicity misdiagnosed as an unresolved tinea manuum infection in a patient evaluated for occupational exposure is reported.
Phytoalexins and other natural products as factors in plant disease resistance
  • J. Ingham
  • Biology, Chemistry
    The Botanical Review
  • 2008
The detection and characterisation of phytoalexins and other related natural products, the elucidation of their biosynthetic pathways and where appropriate their antifungal mechanisms, and the development of these substances or synthetic analogues for use in crop protection provides a new and exciting field of plant pathology which without doubt will be greatly expanded in the years that lie ahead.
Molecular diversity of tuliposide B-converting enzyme in tulip (Tulipa gesneriana): identification of the third isozyme with a distinct expression profile
Identification of TgTCEB-L explains the PosB-converting activity detected in tissues where T gTCEB1 and Tg TCEB-R transcripts could not be detected, indicating that tulip subtilizes the three TGTCEB isozymes depending on the tissue.
Molecular identification of tuliposide B-converting enzyme: a lactone-forming carboxylesterase from the pollen of tulip.
Results indicate that mature TgTCEB1 is specifically localized in plastids of pollen grains, but not in the intracellular spaces of pollen grain, as previously reported.
Influence of soil temperature on field infection of tulip bulbs by Fusarium oxysporum
It is suggested that a high inoculum level built up in the decaying scales of the planted bulb under warm conditions may weaken the tunic barrier by local reduction of the tuliposid concentration in the white tunic, which compound is a precursor of the fungitoxic tulipalin.
A Novel Lactone-Forming Carboxylesterase: Molecular Identification of a Tuliposide A-Converting Enzyme in Tulip1[W]
To the knowledge, TgTCEA is the first identified member of the lactone-forming carboxylesterases, specifically catalyzing intramolecular transesterification in the tulip defensive strategy.
Molecular Diversity of Tuliposide A-Converting Enzyme in the Tulip
Tuliposide A-converting enzyme (TCEA) catalyzes the conversion of 6-tuliposide A to its lactonized aglycon, tulipalin A, in the tulip (Tulipa gesneriana). The TgTCEA gene, isolated previously from


Presence of a substance in the white skin of young tulip bulbs which inhibits growth ofFusarium oxysporum
  • B. Bergman
  • Biology
    Netherlands Journal of Plant Pathology
  • 2007
It is suggested that this substance is protecting the susceptible fleshy bulb scales during the greater part of the growth period and that its diminution during the final weeks enablesF.
Field infection of tulip bulbs byFusatrium oxysporum
  • B. Bergman
  • Biology
    Netherlands Journal of Plant Pathology
  • 2005
Evidence is given that under natural conditions infection more often takes place directly into the fleshy outer scale of the new bulb, often during the last weeks before the bulb skin turns brown.
Isolation and identification of c~-methylene butyrolactone, a fungitoxie substance from tulips
  • Recl Tray. chim. Pays-Bas Belg
  • 1967
Untersuchungen fiber Blfiteninfektionen
  • V. Untersuchungen an Tulpen. Phytopath. Z
  • 1967
Untersuchungen fiber fungistatische Stoffe in der Tulpe und ihre Bedeutung ffir die Blfiteninfektion
  • 1966
alpha-Methylene butyrolactone from Erythronium americanum.