A functioning artificial secretory cell

@inproceedings{Simonsson2012AFA,
  title={A functioning artificial secretory cell},
  author={Lisa Simonsson and Michael E. Kurczy and Rapha{\"e}l Trouillon and Fredrik Hook and Ann-Sofie Cans},
  booktitle={Scientific reports},
  year={2012}
}
We present an amperometric study of content release from individual vesicles in an artificial secretory cell designed with the minimal components required to carry out exocytosis. Here, the membranes of the cell and vesicles are substituted for protein-free giant and large unilamellar vesicles respectively. In replacement of the SNARE-complex, the cell model was equipped with an analog composed of complimentary DNA constructs. The DNA constructs hybridize in a zipper-like fashion to bring about… CONTINUE READING
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