A functional genomic perspective on human well-being

  title={A functional genomic perspective on human well-being},
  author={B. Fredrickson and K. Grewen and Kimberly A. Coffey and Sara B. Algoe and Ann M. Firestine and J. Arevalo and Jeffrey Ma and S. Cole},
  journal={Proceedings of the National Academy of Sciences},
  pages={13684 - 13689}
  • B. Fredrickson, K. Grewen, +5 authors S. Cole
  • Published 2013
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • To identify molecular mechanisms underlying the prospective health advantages associated with psychological well-being, we analyzed leukocyte basal gene expression profiles in 80 healthy adults who were assessed for hedonic and eudaimonic well-being, as well as potentially confounded negative psychological and behavioral factors. Hedonic and eudaimonic well-being showed similar affective correlates but highly divergent transcriptome profiles. Peripheral blood mononuclear cells from people with… CONTINUE READING
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