A functional anatomical study of unipolar depression.

  title={A functional anatomical study of unipolar depression.},
  author={Wayne C. Drevets and Tom O. Videen and Joseph L. Price and Sheldon H. Preskorn and S Thomas Carmichael and Marcus E. Raichle},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={12 9},
The functional neuroanatomy of unipolar major depression was investigated using positron emission tomography to measure differences in regional cerebral blood flow (BF). A relatively homogeneous subject group was obtained using criteria for familial pure depressive disease (FPDD), which are based upon family history as well as upon symptoms and course. Because of the absence of certain knowledge about the pathophysiology of mood disorders and their underlying functional neuroanatomy, we used… CONTINUE READING
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