A functional analysis of a natural variant of intercellular adhesion molecule-1 (ICAM-1Kilifi).

Abstract

Intercellular adhesion molecule-1 (ICAM-1) is involved in a range of interactions both within the host and between the host and a number of pathogens. Recently we described a mutation within the coding region of the first N-terminal immunoglobulin-like domain of ICAM-1, present at high frequency within African populations, which increased the risk of… (More)

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