A full-genome phylogenetic analysis of varicella-zoster virus reveals a novel origin of replication-based genotyping scheme and evidence of recombination between major circulating clades.

@article{Peters2006AFP,
  title={A full-genome phylogenetic analysis of varicella-zoster virus reveals a novel origin of replication-based genotyping scheme and evidence of recombination between major circulating clades.},
  author={Geoffrey A. Peters and Shaun D. Tyler and Charles Grose and Alberto Severini and Michael J Gray and Chris Upton and Graham A. Tipples},
  journal={Journal of virology},
  year={2006},
  volume={80 19},
  pages={9850-60}
}
Varicella-zoster virus (VZV) is a remarkably stable virus that until recently was thought to exhibit near-universal genetic homogeneity among circulating wild-type strains. In recent years, the expanding knowledge of VZV genetics has led to a number of groups proposing sequence-based typing schemes, but no study has yet examined the relationships between VZV genotypes at a full-genome level. A central hypothesis of this study is that VZV has coevolved with humankind. In this study, 11… CONTINUE READING

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