• Corpus ID: 249192054

A full contraction-reaction-diffusion model for pattern formation in geometrically confined microtissues

  title={A full contraction-reaction-diffusion model for pattern formation in geometrically confined microtissues},
  author={Tiankai Zhao and Hongyan Yuan},
The reaction-diffusion models have been extensively applied to explain the mechanism of pattern formations in early embryogenesis based on geometrically confined microtissues consisting of human pluripotent stem cells. Recently, mechanical cues, such as the cellular stresses and strains, have been found to dictate the pattern formation in human stem cell differentiation. As a result, the traditional reaction-diffusion models are modified by adding mechanically related terms to consider the role… 

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