A frequent oligogenic involvement in congenital hypothyroidism.


Congenital hypothyroidism (CH), the most frequent form of preventable mental retardation, is predicted to have a relevant genetic origin. However, CH is frequently reported to be sporadic and candidate gene variations were found in <10% of the investigated patients. Here, we characterize the involvement of 11 candidate genes through a systematic Next… (More)
DOI: 10.1093/hmg/ddx145


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