A free radical theory of male infertility.

@article{Aitken1994AFR,
  title={A free radical theory of male infertility.},
  author={Robert John Aitken},
  journal={Reproduction, fertility, and development},
  year={1994},
  volume={6 1},
  pages={19-23; discussion 23-4}
}
There is a growing body of evidence to indicate that a significant factor in the aetiology of male infertility involves a loss of sperm function as a consequence of oxidative stress. This stress originates from the excessive generation of reactive oxygen species by the spermatozoa and results in the peroxidation of unsaturated fatty acids in the sperm plasma membrane. It is possible that reactive oxygen species originating from infiltrating leucocytes could also stress the spermatozoa although… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 75 extracted citations

Effects of vitamin E supplementation in the extender on frozen-thawed bovine semen preservation.

Animal : an international journal of animal bioscience • 2011
View 9 Excerpts
Highly Influenced

Selenium in human male reproductive organs.

View 4 Excerpts
Highly Influenced

Assessing the male in fertility clinics—men undervalued, undermanaged and undertreated

Translational andrology and urology • 2017
View 3 Excerpts
Highly Influenced

Preimplantation embryotoxicity after mouse embryo exposition to reactive oxygen species.

Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al • 2007
View 4 Excerpts
Highly Influenced

UCP2 Mitigates the Loss of Human Spermatozoa Motility by Promoting mROS Elimination.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology • 2018

Similar Papers

Loading similar papers…