A framework and model system to investigate linear system behavior in Escherichia coli

@inproceedings{Hajimorad2011AFA,
  title={A framework and model system to investigate linear system behavior in Escherichia coli},
  author={Meghdad Hajimorad and Paul R. Gray and Jay D Keasling},
  booktitle={Journal of biological engineering},
  year={2011}
}
BACKGROUND The ability to compose biological systems from smaller elements that act independently of the other upon assembly may help make the forward engineering of biological systems practical. Engineering biology in this manner is made difficult by the inherent nonlinear response of organisms to genetic devices. Devices are inevitably coupled to one another in the cell because they share the same transcriptional machinery for expression. Thus, new properties can emerge when devices that had… CONTINUE READING
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Two of the devices encoded the bacterial neomycin phosphotransferase II ( nptII ) and chloramphenicol acetyl transferase ( cat ) , while the third encoded the jellyfish - originating green fluorescent protein ( gfp ) .
Two of the devices encoded the bacterial neomycin phosphotransferase II ( nptII ) and chloramphenicol acetyl transferase ( cat ) , while the third encoded the jellyfish - originating green fluorescent protein ( gfp ) .
Two of the devices encoded the bacterial neomycin phosphotransferase II ( nptII ) and chloramphenicol acetyl transferase ( cat ) , while the third encoded the jellyfish - originating green fluorescent protein ( gfp ) .
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