A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

@article{Ogura2001AFM,
  title={A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease},
  author={Y. Ogura and D. Bonen and N. Inohara and D. Nicolae and Felicia F. Chen and R. Ramos and Heidi M. Britton and Thomas Moran and Reda Karaliuskas and R. Duerr and J. Achkar and S. Brant and T. M. Bayless and B. Kirschner and S. Hanauer and G. N{\'u}{\~n}ez and Judy H. Cho},
  journal={Nature},
  year={2001},
  volume={411},
  pages={603-606}
}
  • Y. Ogura, D. Bonen, +14 authors Judy H. Cho
  • Published 2001
  • Biology, Medicine
  • Nature
Crohn's disease is a chronic inflammatory disorder of the gastrointestinal tract, which is thought to result from the effect of environmental factors in a genetically predisposed host. A gene location in the pericentromeric region of chromosome 16, IBD1, that contributes to susceptibility to Crohn's disease has been established through multiple linkage studies, but the specific gene(s) has not been identified. NOD2, a gene that encodes a protein with homology to plant disease resistance gene… Expand
4,712 Citations
Editorial: The CARD15 gene mutation in Crohn disease
  • M. Vatn
  • Medicine
  • Scandinavian journal of gastroenterology
  • 2003
The Nod2 Gene in Crohn's Disease: Implications for Future Research Into the Genetics and Immunology of Crohn's Disease
  • J. Cho
  • Biology, Medicine
  • Inflammatory bowel diseases
  • 2001
  • 50
  • PDF
Lessons to be learned from the NOD2 gene in Crohn's disease
  • 54
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 29 REFERENCES
Mapping of a susceptibility locus for Crohn's disease on chromosome 16
  • 1,003
Human Nod1 Confers Responsiveness to Bacterial Lipopolysaccharides*
  • 540
  • PDF
Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: evidence for epistasis between 1p and IBD1.
  • J. Cho, D. Nicolae, +13 authors S. Brant
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1998
  • 413
  • PDF
Genetic complexity of pathogen perception by plants: the example of Rcr3, a tomato gene required specifically by Cf-2.
  • 159
  • PDF
TLR4 mutations are associated with endotoxin hyporesponsiveness in humans
  • 2,011
...
1
2
3
...