A frame shift mutation in a hot spot region of the nuclear autoantigen La (SS-B).

@article{Bachmann1996AFS,
  title={A frame shift mutation in a hot spot region of the nuclear autoantigen La (SS-B).},
  author={Michael Bachmann and Helmut Troester and Helmut Bartsch and Daniel Gr{\"o}lz},
  journal={Journal of autoimmunity},
  year={1996},
  volume={9 6},
  pages={747-56}
}
A hot spot region was identified in the exon 7 of the nuclear autoantigen La (SS-B). Two La cDNAs were identified which contained a frame shift mutation in the hot spot region. One La cDNA was isolated from a cDNA library made from peripheral blood lymphocytes of an autoimmune patient with primary Sjögren's Syndrome, the other La cDNA was isolated from a… CONTINUE READING