A four PDZ domain-containing splice variant form of GRIP1 is localized in GABAergic and glutamatergic synapses in the brain.

@article{Charych2004AFP,
  title={A four PDZ domain-containing splice variant form of GRIP1 is localized in GABAergic and glutamatergic synapses in the brain.},
  author={Erik I Charych and Wendou Yu and Rongwen Li and David R. Serwanski and Celia P. Miralles and Xuejing Li and Bih Y Yang and Noelia Pinal and Randall Walikonis and Angel L. De Blas},
  journal={The Journal of biological chemistry},
  year={2004},
  volume={279 37},
  pages={38978-90}
}
We have isolated, from a rat brain cDNA library, a clone corresponding to a 2779-bp cDNA encoding a novel splice form of the glutamate receptor interacting protein-1 (GRIP1). We call this 696-amino acid splice form GRIP1c 4-7 to differentiate it from longer splice forms of GRIP1a/b containing seven PDZ domains. The four PDZ domains of GRIP1c 4-7 are identical to PDZ domains 4-7 of GRIP1a/b. GRIP1c 4-7 also contains 35 amino acids at the N terminus and 12 amino acids at the C terminus that are… CONTINUE READING